Zika Virus Infection during Pregnancy and its Management

Zika virus (ZIKV) is a mosquito-borne Flavivirus having perilous effects globally, and more particularly among pregnant females. Its current epidemic in the Pacific and in Central and South America is linked with microcephaly and other abnormalities of the central nervous system in neonates. The case reports and personal communications are the only sources containing data about ZIKV and pregnancy; however, recommendations related to managing ZIKV exposure during pregnancy are emerging rapidly. We aim to review and synthesize the existing literature about ZIKV and pregnancy and to assist clinicians to manage pregnant patients who are susceptible to ZIKV infection. This review supports the existing evidence about the causal link between microcephaly and ZIKV infection during pregnancy. Globally more than 2 billion people are the residents of the areas which are conducive to ZIKV transmission. It is estimated that in 2016 around 4 million people will be infected with ZIKV in the Americas. Looking towards the current scenario of ZIKV pandemic and its drastic consequences during pregnancy, it is quite evident that ZIKV may have massive impact both on health services and affected communities. Thus, there is a dire need to establish global public health and research response on urgent footing to minimize and preclude its deleterious impact via proper diagnosis, vaccination and treatment.


Muhammad Rehan Sarwar and Anum Saqib

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